Aim: To compare the histomorphological changes in the precentral gyrus of cerebral cortex of albino rats by taking green tea and black tea aqueous extract.

Study design: Experimental Study

Duration of study: 30 days study conducted in Animal Experimental Research Laboratory of PGMI and Department of Anatomy, King Edward Medical University, Lahore.

Methodology: 90 albino rats were divided into three groups of 30 animals each. Rats in the group I were given distilled water, while group II and group III received green tea and black tea aqueous extract respectively. At the end of 30 days of experiment, brains were removed and studied for histological changes.

Results: When comparison among all the three groups was made at 30 days time, p-value was significant for gliosis i.e. p<0.01. However, experimental group III revealed more gliosis among all the three groups. Necrosis was absent in all the groups and was not statistically analyzed.

Conclusion: Gliosis caused by black tea is highly significant as compared to green tea.

Key words: Cerebral Cortex, Green tea, Black tea, Gliosis, Necrosis