Background: Lichen planus is a disease that can involve either skin, mucosa or both. Although there is no definite treatment but many medications are available for the relieving the symptoms of this autoimmune disease and recent literature has brought into light the use of an immunosuppressant such as Tacrolimus that may be effectively used as topical application in treatment of Oral Lichen Planus (OLP).

Methods: We conducted a study on 80 patients to determine the use of results of topical Tacrolimus (0.1%) versus Triamcinolone acetonide (0.1%) ointment for the treatment of Oral Lichen Planus over a period of six months at Oral & Maxillofacial Surgery Department, HITEC Dental College Taxila.

Results: Outcome of the study was determined in terms of ‘Improvement in pain’.

Conclusion: This study showed an insignificant difference in improvement in pain of patients of lichen planus treated with tacrolimus and triamcinolone.

Keywords: Oral lichenplanus, treatment outcome, symptomatic management, improvement in pain,