ABSTRACT

Background: The frequency of End Stage Renal Disease (ESRD) is rising globally and it has grown into an important public health problem. Left ventricular hypertrophy (LVH) is cardiac problem in which the myocardium of left ventricle becomes thickened. Anaemiais defined as the reduction in the quantity of the hemoglobin and the red blood cells. Anemia is one of the known contributory factors for the development of LVH.

Aim: To assess the association of Left ventricular hypertrophy with Anemia in patients on maintenance hemodialysis as detected by echocardiography

Methods: This cohort study was conducted at Sheikh Zayed Hospital’s Dialysis Centre, Lahore for 1 year. The Non probability purposive sampling technique was used to include the patients of ESRD on Hemodialysis. Informed consent was taken from all the patients.

Results: In our study, the overall mean age was 46.4±13.1 years. There were 35 (58.3%) males in anemic and 33(55.0%) in non-anemic group. The LVH size for anemic group was 10.2±2.9 mm while for non-anemic was 8.2±1.4 mm. The LVH was found to be present in 32(53.3%) of anemic while in only 2(3.3%) of non-anemic cases. Risk of LVH in about 3 times high in ESRD patients with anemia i.e., RR=2.89 95%CI; 2.108, 3.963).

Conclusion: Our study results concluded that significant association was found between the Left ventricular hypertrophy with Anemia in patients on maintenance Hemodialysis as detected by echocardiography; however, Odd Ratio (OR) showed more risk in anemic patients as compared to other.

Keywords: Left ventricular hypertrophy, Anemia, Hemodialysis, Hemoglobin, ESRD