ABSTRACT

Objective: To determine the outcome of peripartum cardiomyopathy and evaluation of the risk factors, clinical and radiological findings in patients admitted at GMC Sukkur.

Material and Methods: This descriptive study was conducted from August 2018 to December 2019 at the Gynecology/Obstetrics Department, and the Cardiology department of Ghulam Muhammad Mahar Medical College, Sukkur. Patients between age of 15 to 50 years, presented with clinical features suggestive of heart failure, either in late pregnancy, i.e. one month pre-partum or within the first five months postpartum, without any identifiable cause of heart failure, were included. Peripartum cardiomyopathy was diagnosed on the basis of signs and symptoms, and confirmed by electrocardiogram, echo and chest X-ray. The collected data were analyzed using SPSS version 26.

Results: A total of 82 patients were studied, their mean age was 31.0±4.15 years. The most common risk factor was multiparty (59.7%), followed by age above 30 (58.5%) years. Hypertension was present in 48.7% participants; diabetes was present in 32.9% participants and maternal mortality was 18.2%. The most common complication was congestive cardiac failure (26.8%), followed by arrhythmias. 18.0% fetus were stillbirth. Neonatal mortality was 5.9% and 42.6% of alive birth required neonatal intensive care unit admission.

Conclusion: Maternal and fetal outcome was observed in the patients of Peripartum cardiomyopathy. Maternal age and multiparty were prominent risk factors for peripartum cardiomyopathy. It is important that efforts should be made to identify the women at risk of peripartum cardiomyopathy early in pregnancy. Multidisciplinary teams should manage pregnant women at risk of peripartum cardiomyopathy.

Keywords: Peripartum Cardiomyopathy, Risk Factors, Maternal Outcome, Fetal Outcome

August 2018 to December 2019. A total of eighty-two women