Gianotti-Crosti Syndrome in a Child with Recent Covid-19 Infection: A Case Report
Youssef A. Alqahtani, Ayed A. Shati, Ahmad A. Alhanshani, Faisal H. Tobeigei, Saleh M. Alqahtani
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ABSTRACT
Gianotti-Crosti
Syndrome is a rare skin disease affecting children at the first years of age.
The condition is clinically featured by blisters on the skin of the legs,
buttocks and arms. A history of viral infection preceding the disease was
reported for many cases. A 12-month-old boy, free of any medical
illnesses, was presented with a history of acute-onset rash for five days prior
to presentation that was preceded by a history of fever for two days then
subsided. The rashes appeared initially on his buttocks, then spread to his
upper and lower extremities and trunk. The child had fever, sore throat and
coryza symptoms with lethargy. A
polymerase chain reaction (PCR) swab was taken to test for SARS-CoV-2, which
was positive two weeks before rash onset. All symptoms resolved in 1 week with
supportive therapy and the current rashes appeared two weeks later in the
patient. Gianotti–Crosti syndrome may
follow the active phase of infection for some cases. It should not be
misdiagnosed with dermatological simple eruptive disorders. The clinical
features for covid-19 associated infection are typical for the well-known
clinical picture of the syndrome. The case was reported to improve clinicians’
awareness and help in better understanding and reporting cutaneous
manifestations of COVID-19.
Keywords: Gianotti-Crosti
Syndrome; Infants; Children; covid-19; Corona