Nagina Bibi, Iram Inam, Ghiasul Hassan

Association of Thyroid Dysfunction and Pregnancy Outcomes

Nagina Bibi, Iram Inam, Ghiasul Hassan



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ABSTRACT

Background: Hypothyroidism in pregnancy results in serious consequences for both mother and fetus. Pregnant women are prone to thyroid dysfunction due to physiological changes taking place in body. This study is undertaken to see the effect of thyroid dysfunction on pregnancy outcomes.

Methodology: A prospective observational study was done. Study was conducted in a private gynecological and obstetric unit. A sample size of 200 women in selected institute with singleton pregnancy was recruited. Pregnant women with chronic disabilities and previously known thyroid disorders were excluded. Data was analyzed using SPSS version 23.0 and binary logistic regression analysis was done. Ethical rules were followed throughout the study and consent taken from all participants.

Results: Out of 200, 23 participants were positive for thyroid disorder. Thyroid dysfunctions are responsible for causing multiple complications in pregnancy for mother and fetus. Findings suggest a signification association of thyroid dysfunction and feto-maternal consequences (p-value <0.005).

Conclusion: Subclinical hypothyroidism is a common finding during pregnancy. It is compulsory to detect and treat thyroid dysfunction early in pregnancy so that adverse outcomes could be avoided. There is a need for timely screening of thyroid profile in suspected pregnancies.

keywords: TSH, FT3, FT4, Pregnancy, Outcomes.



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