Frequency of Isolation and Antibiotic Susceptibility of Micro-Organisms Causing Urinary Tract Infections in Children
Saima Pervaiz, Sadia Ikram, Anila Errum, Sahar Iqbal, Sara Massood Cheema, Nida Javed, Saba Shamim
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ABSTRACT
Objective: To determine the frequency of urinary tract infections and the spectrum of microorganisms causing UTI and their antibiotics susceptibility pattern in children age between 1 month and 12 years.
Patients and Methods: In this cross-sectional study, 131 patients of suspected UTI, from the department of pediatric medicine were included, from June-2020 to Nov-2020. 5 milliliters of urine sample were collected and sent to the hospital laboratory for determination of UTI. If UTI was confirmed, samples were further processed to determine the pattern of organisms causing UTI and their antibiotic spectrum.
Results: Mean age of the patients included in this study was 6.07±256 years. There were 75 (57.25%) male patients, and 56 (42.75%) female patients. Urinary tract infections were diagnosed in 30 (22.90%) patients. E. coli diagnosed in 14 (46.67%) patients. Resistant strains were diagnosed in 3 (10%) patients. Regarding antibiotic sensitivity, 3rd generation cephalosporins and carbapenems were sensitive to many organisms.
Conclusion: E. coli is the predominant uropathogen causing UTIs in children. Third generation cephalosporins are optimal initial choice for management of UTI in children.
Keywords: urinary tract infections, causating micro-organisms, antibiotic sensitivity.