Tuberculous Cervical Lymphadenitis: Diagnosis and Treatment Outcomes
Abdul LatifKakar, RizwanaRehmanBazai, AsmatullahAchakzai, Muhammad ArifAchakzai, JahanZaibKakar
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ABSTRACT
Aim: To examine
the frequency of tuberculosis lymphadenitis by fine needle aspiration biopsy
and histopathology in patients with cervical lymphadenitis also determine the
treatment outcomes of anti-tuberculosis therapy in patients diagnosed to have tuberculosis
cervical lymphadenitis.
Study Design: Prospective/Observational
Place and Duration: Department of ENT and Head & Neck Surgery, Department of Diagnostic Radiology
Civil Hospital Quetta and Yaseen Hospital Quetta from 1st January
2018 to 31st December 2019.
Methods: Sixty patients
of both genders with ages 5 to 65 years presented with cervical lymphadenitis were
enrolled in this study. Patient’s detailed demographic including age, sex, and
clinical presentations were recorded. All patients underwent ultrasound guided fine
needle aspiration biopsy and excisional biopsy to examine the tuberculosis
cervical lymphadenitis. Patients with positive tuberculosis lymphadenitis were
received standard anti-tuberculosis therapy. Treatment outcomes such as cured,
died and lost to follow-up was examined. Follow-up was taken at 9 months.
Results: Thirty
two (53.33%) were males while 28 (46.67%) were females. Majority 25 (41.67%) patients
were ages 21 to 35 years followed by 16 (26.67%) with ages 36 to 50 years. Neck
swelling was found in 60 (100%) patients followed by weight loss and fever in
38 (63.33%) and 24 (40%) patients. 36 (60%) patients had tuberculosis cervical
lymphadenitis while 24 (40%) had other causes of cervical lymphadenitis by
ultrasound guided fine needle aspiration. Among 36 tuberculosis cervical
lymphadenitis patients 28 (77.78%) were females while 8 (22.22%) were males and
mean age of patients was 37.46±11.28 years. From all tuberculosis cervical
lymphadenitis patients 30 (83.33%) patients were cured, 3 (8.33%) were died and
3 (8.33%) were lost to follow-up.
Conclusion: The frequency of tuberculosis cervical lymphadenitis is very high among
cervical lymphadenitis patients. Ultrasound guided FNA biopsy plays an
important role for the diagnosis and management of this malignant disease.
Keywords: Cervical
lymphadenitis, Tuberculosis, Ultrasound-guided fine needle aspiration,
Anti-tuberculosis therapy,
ABSTRACT
Aim: To examine
the frequency of tuberculosis lymphadenitis by fine needle aspiration biopsy
and histopathology in patients with cervical lymphadenitis also determine the
treatment outcomes of anti-tuberculosis therapy in patients diagnosed to have tuberculosis
cervical lymphadenitis.
Study Design: Prospective/Observational
Place and Duration: Department of ENT and Head & Neck Surgery, Department of Diagnostic Radiology
Civil Hospital Quetta and Yaseen Hospital Quetta from 1st January
2018 to 31st December 2019.
Methods: Sixty patients
of both genders with ages 5 to 65 years presented with cervical lymphadenitis were
enrolled in this study. Patient’s detailed demographic including age, sex, and
clinical presentations were recorded. All patients underwent ultrasound guided fine
needle aspiration biopsy and excisional biopsy to examine the tuberculosis
cervical lymphadenitis. Patients with positive tuberculosis lymphadenitis were
received standard anti-tuberculosis therapy. Treatment outcomes such as cured,
died and lost to follow-up was examined. Follow-up was taken at 9 months.
Results: Thirty
two (53.33%) were males while 28 (46.67%) were females. Majority 25 (41.67%) patients
were ages 21 to 35 years followed by 16 (26.67%) with ages 36 to 50 years. Neck
swelling was found in 60 (100%) patients followed by weight loss and fever in
38 (63.33%) and 24 (40%) patients. 36 (60%) patients had tuberculosis cervical
lymphadenitis while 24 (40%) had other causes of cervical lymphadenitis by
ultrasound guided fine needle aspiration. Among 36 tuberculosis cervical
lymphadenitis patients 28 (77.78%) were females while 8 (22.22%) were males and
mean age of patients was 37.46±11.28 years. From all tuberculosis cervical
lymphadenitis patients 30 (83.33%) patients were cured, 3 (8.33%) were died and
3 (8.33%) were lost to follow-up.
Conclusion: The frequency of tuberculosis cervical lymphadenitis is very high among
cervical lymphadenitis patients. Ultrasound guided FNA biopsy plays an
important role for the diagnosis and management of this malignant disease.
Keywords: Cervical
lymphadenitis, Tuberculosis, Ultrasound-guided fine needle aspiration,
Anti-tuberculosis therapy,