ABSTRACT

Aim: To determine the frequency of dyslipidemia in patients presented with ischemic stroke.

Study design: Cross-sectional study.

Place and duration of study: Department of Medicine, Sahara Medical College Narowal in collaboration with Department of Medicine, Govt. Khawaja Muhammad Safdar Medical College Sialkot from 01-01-2020 to 31-12-2020

Methodology: Two hundred patients of both genders with ages between 25-75 years were enrolled. Patient’s detailed demographics age, gender and body mass index were recorded after taking written consent. All patients of ischemic stroke were undergone for CT scan brain. Expert opinion about infarction area in brain was taken from qualified neurologist from Gujranwala Medical College, Gujranwala. Patients having fasting lipid profile [serum triglycerides, low density lipoprotein (LDL), very low density lipoprotein (VLDL), and high density lipoproteins (HDL)], blood sugar levels and serum homocystein levels were measured.

Results: One hundred and sixteen (58%) patients were males and 84(42%) were females. Mean age of the patients were 55.74±4.39 years and mean BMI was 27.87±5.14 kg/m2. Dyslipidemia was found in 110 (55%) patients and among them increased HDL was found in 46 (23%) patients with mean 152.4±14.5, high total cholesterol was found in 42(21%) with mean 217.6±29.8, LDL in 140 (70%) with mean 29.6±5.6, triglycerides 32 (16%) with mean 204.1± 32.2 and elevated non HDL c (>130mg/dl) in 68 (34%) with mean 170.8±22.3.

Conclusion: Dyslipidemia has a very strong correlation with ischemic stroke and the frequency of dyslipidemia in patients presented with ischemic stroke was very high.

Keywords: Ischemic stroke, Serum triglyceride, Serum cholesterol, Dyslipidemia