ABSTRACT

Objective: To determine the renal profile among hypertensive disorder women during pregnancy at tertiary care Hospital.

Material and methods: This prospective study has been conducted at gynaecology and obstetrics department of Liaquat University of Medical and Health Sciences Jamshoro. Study duration was six months from May 2019 to October 2019. All the pregnant women presented with hypertensive disorders including chronic hypertension, pregnancy induced hypertension, Eclampsia and pre-eclampsia, age 18 to 40 years and either of parity were included. A 3ml blood sample was taken from each patient and was sent to the Hospital diagnostic laboratory to the renal function. Serum creatinine level >1.4mg/dl was considered as renal failure. All the data was recorded via self-made study proforma. Data analysis was done by using SPSS version 20.

Results: Total 265 hypertensive disorder pregnant women were studied. Mean age of the women was 32.34+3.65 years and mean gestational age was 30.25+4.77 weeks. Out of all 57.0% women were un-booked and 43.0% were booked. Most of the women 55.2% had pre-eclampsia, followed by eclampsia, PIH and Help syndrome. 47.3% women had grade I parenchymal changes, 21.8% had grade II parenchymal changes, 6.1% had grade III parenchymal changes and in patient septations were found. Urea was raised among 37.0% women elevated creatinine level was in 13.9% females; however out of them mostly had mildly increased urea and creatinine levels.

Conclusions: Renal impairment was found to be frequently prevalent among hypertensive women during pregnancy. By early assessment and management can be reduce the feto-maternal morbidity and mortality among hypertensive pregnant women.

Key words: pre-eclampsia, eclampsia, PIH, creatinine level