ABSTRACT

At the final stage of hemodialysis(HD), the strongest indicator of mortality is hypoalbuminemia. By excluding hypoalbuminemia caused by underlying renal disease or other diseases, the metabolic acidosis causes net negative nitrogen and overall protein balance in the body. Because of insufficient dialysis, some patients going through maintenance dialysis have spuriously low plasma bicarbonate levels. The study aimed to estimate the role of common serum bicarbonate on serum albumin concentration. The case study was performed in Baghdad Educational Hospital/ the Medical City, in the Iraqi Hemodialysis Center. The study group of 100 subjects with ESRD on HD was split up evenly into low albumin levels and control with normal albumin levels before and after HD sessions. VBG was done for every patient in study groups and hco3 to measure the Kt/V and show the adequacy of dialysis and take information about the number and duration of dialysis sessions. (The result shows an important correlation between low albumin levels and low hco3 in patients with HD and between dialysis session with albumin) still unclear to me. Hypoalbuminemia is also substantially correlated with low Kt\V. However, according to the logistic regression model, it tends to be dependent on the existence of other hypoalbuminemia risk factors. Age and sex are not statistically significant with hypoalbuminemia.

Conclusions: A significant amount of evidence indicates that metabolic acidosis that has not been corrected is detrimental to overall health. Independent and significant associated with hypoalbuminemia in maintained hemodialysis (MHD) patients indicate the metabolic acidosis exerts a detrimental effect on the nutritional condition of patients with MHD.