ABSTRACT

Background: This is a cross sectional study carried out in the department of medicine (Cardiology Division), Allied Hospital Faisalabad. In this study, almost 60 cases were analyzed to identify abnormalities associated with cardiovascular system in the thyrotoxicosis.

Objective: The aim of the study was to evaluate the importance as well as prevalence of cardiovascular abnormalities in the patients having thyrotoxicosis.

Settings and Design: This study was executed in tertiary care hospital within a period of approximately one year in which 60 cases were taken. 15 subjects were males while 45 subjects were females. This study includes the subjects of age within 15 – 83 years.

Methods and Material: The study involves cases of newly diagnosed thyrotoxicosis that were analyzed on the basis of information collected on taking history, physical examination and cardiovascular examination as well as investigation, hormonal evaluation, complete profile of biochemistry, radiographs of chest and ECG (12- lead), ECHO (mode/2 dimensional / colored Doppler US).Percentages were calculated according to the qualitative data to make descriptive analysis. In order to evaluate quantitative variables, standard deviation as well as mean were evaluated for calculation and report formation.

Results: About 60 subjects were taken of which 46.1 years was mean age and the range was between 15-83 years and 75% were females. The presentation of fatigue and weakness was 100 percent present in all the patients along with breathlessness, palpitations, weight loss contributing about 92 percent, hypertrophy of ventricles (42 percent), congestive heart failure (40 percent), arrythmias and cardiomegaly contributing about (30 percent) and (25 percent) with bundle branch block.

Conclusion: The prognostic factors and the results of cardiovascular disease is associated with early treatment or management with hormonal control. Therefore, thyrotoxicosis related cardiovascular abnormalities must be evaluated.

Key words: Thyrotoxicosis, hyperthyroidism, cardiovascular abnormalities