Nasma Wabasa, Delima Maria, Kamran Naseem, Naima Mujahid, Arshad Faheem, Sumaira Aslam

Positive Predictive Value of Contrast Enhanced- Fluid Attenuated Inversion Recovery (CE -Flair) MRI in Diagnosing Meningitis

Nasma Wabasa, Delima Maria, Kamran Naseem, Naima Mujahid, Arshad Faheem, Sumaira Aslam



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ABSTRACT

Aim: PPV of contrast enhanced fluid - attenuated inversion recovery (CE -FLAIR) MRI for diagnosis of meningitis considering CSF as gold standard

Study Design: It is a cross-sectional study

Setting & duration: Radiology department,, BVH, Bahawalpur 01-01- 2019 to 30- 06- 2019

Methods:  A total of 130 patients having signs & symptoms of meningitis for last 72 hours with age group 15-50 years were included. MRI was performed on a 1.5 tesla MR System.  The MRI protocol included the T1W SE sequence, the T2W SE sequence, the T1W sequence wit h FS, the FLAIR sequence. The CE-FLAIR, T1W sequences wit h  MT   and  FS  were obtained  after administration of intravenous gadobutrol in a dose of 0.1mmo l/kg body weight. After this, lumbar puncture was done and CSF was sent to the laboratory for analysis.  CE -FLAIR MRI findings were correlated with CSF report.

Results: All the patients were subjected first to CE-FLAIR MRI. CE-FLAIR MRI supported the diagnosis of meningitis in 80 (61.5%) patients. CSF confir med meningitis in 71 (true positive) cases where as 09 (False Positive) had no meningitis on CSF. PPV of CE -FLAIR MRI in diagnosis of meningitis was 88.8%.

Conclusion:  PPV of CE -FLAIR MRI in diagnosing meningitis is quit e high.

Keywords: Meningitis, CE -FLAIR MRI 



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