Objectives: To determine the frequency of different C-reactive protein levels in hemodialysis patients having anemia at baseline, taking erythropoietin for the correction of anemia.

Methodology: A cross sectional study was conducted at the Department of Nephrology, Jinnah Hospital Lahore between October 2019 to April 2020. Eighty patients fulfilling the criteria were enrolled after taking informed consent. Demographic information was obtained. Blood samples were taken under aseptic measures. All samples were sent to the laboratory for CRP. The data was analyzed by using SPSS version 20.0.

Results: According to the results of our study, the mean age of patients was 47.50 +16.37 years. With regards to CRP levels, 23.7% patients had CRP < 1.3 mg/l, 22.5% patients had CRP of 1.3-2.04 mg/l, 26.25% had CRP of 2.05-3.21 mg/l and 27.5% patients had >3.21 mg/l. Further analysis showed that CRP was not significantly different in different age groups i.e. p=0.862 but CRP levels were significantly different in males and females(Chi square:7.214)  i.e. p value = 0.027.

Conclusion: CRP is high in most CKD anemic patients who are on hemodialysis and taking erythropoietin.

Keywords: Hemodialysis, CRP, Erythropoietin.