Melasma and its Association with Serum Iron Levels and Complete Blood Count
Rahila Aamir, Aqsa Naheed, Aashi Ahmed, Tehzeeb Zehra, Bilqees Fatima, Ambreen Javed, Nasser Rashid Dar
352
ABSTRACT
Objective: To observe association
of Melasma with serum Iron and complete blood count indices
Study
Design: Case-control
cross-sectional study
Place and Duration of Study: Department
of Dermatology, HIT Hospital Taxila
from 1st May 2021 to 1st
October 2021
Methodology:
Fifty seven females having melasma were taken as
cases and 48 non-pregnant females without melasma as control between 12-50
years of age.
Women with pregnancy, history of cardiac or thyroid disease and usage of
hormone therapy, phototoxic drugs or anti-convulsant drugs were not included.
History and examination was done by a dermatologist. Modified MASI (m Melasma Area and Severity Index) score was
used for assessing severity of melasma. Blood samples
were collected and send for serum Ferritin level, TIBC and
Complete blood count in both groups.
Results: The mean
age of females were 35±7.4 years, and 48 female patients with no melasma were
selected as controls with mean age of 25.7±8.4 years. We also analyzed the
effect of different hematological and general factors on mMASI score within
group of melasma patient but again found no statistically significant effect of
any of these on MASI score.
Conclusion:
There is no direct association between
melasma, serum iron levels and blood indices.
Keywords: Melasma, Serum ferritin levels, Complete blood count