Frequency of High MELD Score in Cirrhotic Patients undergoing Liver Resection due to Hepatocellular Carcinoma
Muhammad Omer Farooq, Niaz Ahmed, Hassan Nadeem, Kashif Rafi, Sadia Jabbar, Asmat Ullah
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ABSTRACT
Objective: To determine the
frequency of high MELD score in cirrhotic patients undergoing liver resection
due to hepatocellular carcinoma also compare the frequency of mortality in
patients with high or low MELD score.
Study Design: Cross sectional study
Place and Duration: Department of
Gastroenterology, Shaikh Zayed Hospital, Lahore. Duration: 6months i.e. 23
12-2017 to 22-06-2018.
Methodology: 75 patients were
enrolled. Then blood sample was obtained. Reports assessed and MELD score
calculated. Scores were labeled as high or low. Patients underwent liver
resection according to BCLC. The mortality was noted. All the collected data
was entered and analyzed on SPSS version 22.
Results: In this study out of
total 75 cases 60 were males and 15 females. The mean age of patients was
39.44±9.76 years, male to female ratio was 4:1. Low MELD class was noted in 45
(60%) cases and high MELD class noted in 30(40%) cases. Mortality occurred in
27(36%) cases. Insignificant difference found between the MELD class with
mortality.
Conclusion: High MELD score was
seen in 40% cirrhotic patients undergoing liver resection due to HCC. Post HCC
resection, mortality occurred in 36% patients within three months of surgery.
No significant association was found between the mortality and MELD score.
Keywords: MELD, Hepatocellular Carcinoma, Mortality,
Cirrhosis