Aim: To compare the efficacy of prophylactic bolus dose of ephedrine 10mg to prevent hypotension after spinal anesthesia for elective caesarean section.

Methods: The study was conducted in Gynecological operation theatre suite of Bahria international teaching Hospital Lahore, from 15th September 2020 to 14th January 2021. It was quasi experimental study. It was conducted on ninety women admitted in gynecology department of Bahria international teaching Hospital Lahore, for caesarean delivery. These women were divided randomly into 2 groups: a) Patients in group E10 received ephedrine 1ml from 5ml syringe containing ephedrine 10mg/mland b)’

Results: Patients in group R acted as a control group and received normal saline 1ml from 5ml syringe.Blood pressure was recorded every minute for first 3 minutes, every 2 minutes for next 6 minutes, and then every 3 minutes till the procedure was completed. The sampling technique used was purposive sampling.

Conclusion: It was concluded that prophylactic intravenous ephedrine bolus 10mg is more effective in preventing hypotension than fluid preload alone. It is simple and effective means of reducing the incidence of hypotension undergoing C- section in spinal anaesthesia.

Keywords: Ephedrine, Hypotension, Spinal anesthesia