Background: Fine needle aspiration cytology (FNAC) is used as a diagnostic tool for masses or lumps. Ultrasound-guided FNAC is usually used for the diagnosis of hepatic lesions.

Aim: To analyze the role of ultrasound-guided fine needle aspiration cytology in the differentiation of hepatic lesions in benign and malignant lesions.

Methods: During one year total 83 cases were selected and their FNAC was performed. Cases were analyzed after routine staining. Cell blocks were prepared where blood stained material was aspirated.

Results: Mean age of the patients was 52±7.8 years and M: F of 1.3:1. 8 cases (9.64%) had low cellularity smear, 18 cases (21.69%) were of benign origin and 57 cases (68.67%) revealed malignant lesions, eight cases (9.64%) were of primary origin and 51 cases (59.03%) were of secondary origin.

Conclusion: Ultrasound-guided FNAC is a useful and accurate method and can be used for diagnosis of different kinds of hepatic lesions.

Keywords: Hepatic lesions, Ultrasound-guided fine needle aspiration cytology, cell blocks,