ABSTRACT

Objective: To determine the prevalence of insulin resistance in patients presenting with acne at Tertiary Care Hospital, in Punjab.

Methods: Cross sectional descriptive study was used in department of Dermatology, Combined Military Hospital, Lahore from 26th March 2016 to 25th September 2016.

A total of 110 patients with acne on the basis of Global Acne Grading System for more than 2 year and on treatment were included in the study. Blood sample was collected for serum fasting blood sugar and fasting insulin level. HOMA-IR >2.5 was labelled as insulin sensitivity. SPSS 21 was used for data analysis. Descriptive statistics were calculated. Stratification was done by applying chi-square test. P≤0.05 was considered as significant.

Results: There were 29 male and 81 female patients. Mean age was 30.80±6.42 years. 30.0% patients were smokers. Insulin resistance was observed in 41(37.3%) patients. No significant association of insulin resistance was observed with gender, age, duration of acne, socioeconomic status, and smoking. Conclusion: High prevalence (37.3%) of insulin resistance was observed in patients with ACNE, mostly in females and with longer duration of acne.

Keywords: Prevalence, Insulin Resistance, Acne