ABSTRACT

Objective: Comparing the diabetic patients to non-diabetic in terms of flare-up during endodontic treatment.

Material and Methods: This cross-sectional comparative study was conducted at department of Operative Dentistry, Liaquat University of Medical and Health Sciences Jamshoro/Hyderabad, from June 2015 to April 2016. The study included both the non-diabetic and diabetic individuals with periapical or pulpal pathosis who received orthodontic management on all teeth excluding the third molars, ranging in age from 15 to 75 years and of any gender. After the administration of local anaesthesia, a flexible dam was used. Access cavity was made using high speed handpiece containing diamond bur, which was disinfected using NaOCL 2.25%, Radiographic method was used to determine working length, coronal flaring was performed using G.G burs, K-files were used for apical preparation using step back method, canal was irrigated using NaOCL, temporization of tooth was done using intra-canal placement (CaOH) for 7 days, flare-up was observed for one week after RCT initiation. On next visit of patients intra-canal medications were removed by gentle filing and irrigation. X-rays were taken to assess whether intracanal medication has removed completely and then using paper points canal was dried, obturation was performed using guttapercha and (sealer) selapex via lateral condensation. Once again flare-up was observed for 1 week following obturation; patients were provided the proforma to daily mark pain level according VAS for up to 7 days.

Results: The study included overall 100 patients, equally divided into two groups i.e., diabetics and non-diabetics. The mean age of all study subjects was 35.37+3.12 years, with predominance of female gender (61%). Diabetic patients were found to have significantly more Flare up (day 1st to day-5th) than the non-didactic study subjects (p<0.05). Nearly all diabetic study subjects exhibited good response on day 5th and only 1 case was found to have Flare up with complain of severe pain. In both of the groups, flare up was reduced almost completely on day 6th and day 7th day. As per VAS, comparison of mean pain revealed rapid decline of pain in non-diabetic study subjects, showing significant variance from day 1 to day 5; P-value 0.001. Conclusion: It was concluded that association of flare-up was statistically more significant with diabetics than the non-diabetics following endodontic treatment