ABSTRACT

Aim: The study's objectives were to explain the most common fetal complication in preeclampsia. Understand the different between tunica media and internal area of spiral artery by image J. Mode of delivery associated with PE and Period of pregnancy associated with PE.

Methods : A total of thirty placentas were examined, of those fifteen were taken from healthy mothers and fifteen from mothers with hypertension (preeclampsia). Placentas were collected from the Labor Room and Operation Theatre of Babylon maternity and Paediatric hospital. Transverse cuts were made through the maternal surface at a distance of 2 cm of tissue from the center of each placenta and fixed at 10 per cent of the formal saline content. The tissue was processed and paraffin embedded, and using the rotator microtome, 5 micron serial sections were produced. Hematoxylin and eosin (H&E) stained the tissue parts for analysis. then read the difference between tunica media and internal area by image J program.

Results: The histomorphological study of the placenta spiral artery of pregnant women with preeclampsia showed a significant in different of internal area and tunica media of the spiral artery with P value of 0.04 , 0.015 respectively. There was a significant association between low weight at birth (fewer than 2.5 kg ) and the mode of natural delivery of the control group when p value (<0.001) comparative with the disease group.

Conclusions: Cesarean section is the most common mode of childbirth for women with preeclampsia; the observed and comparative histomorphological changes suggest a decrease in all aspects of the Preeclampsia placenta, as well as an impact on the baby's body weight (less than 2.5 kg) after birth, and dilation of the internal region and tunica media of the spiral artery in the PE placenta.

Keywords: placenta, internal area, tunica media, spiral artery, body weight , mode of delivery , preeclampsia