ABSTRACT

Aim: To determine the effectiveness of dexmedetomidine on the spinal anaesthesia as an adjuvant to the hyperbaric levobupivacaine in patients undergoing cesarean section. Study Design: Comparative/observational

Place and duration of study: Department of Anaesthesia, Akhtar Saeed Medical & Dental College Lahore from 1st October 2019 to 31st March 2020.

Methodology: Ninety cases were included and patients had received comprehensive demographics. Three equal classes of patients were divided into groups A, B and C. Group A had 30 patients and received 2.5 ml isobaric levobupivacane, group B with 30 patients and received 2.5 ml isobaric levobupivacaine, 5μg dexmedetomidine, and group C received 2.5 ml isobaric levobupivacaine and 25 μg fentanyl intrathecally. The outcomes of these groups were analysed in which sensory and motor blockage period were measured from the time the intrathecal drugs were administered.

Results: The mean ages of the patients in group A was 28.78±3.22 years with body mass index 24.18±3.92 kg/m2, in group B was 28.12±4.68 years with body mass index 23.65±3.44 kg/m2 and in group C was 28.95±3.16 years with body mass index 23.44±3.65 kg/m2. Duration of sensory and motor blockade was observed and resulted that it was earlier in group C as compared to group A and B. Prolonged duration of sensory and motor blockade was observed in group B as compared to groups B and C with significantly P value< 0.001.

Conclusion: An adjuvant of 0.5% isobaric levobupivalacaine, Intrathecal dexmedetomidine induces both prolonged motor blockage and post operative analgesia than fentanyl.

Key words: Levobupivacaine, Spinal anesthesia, Fentanyl, Intrathecal analgesia, Cesarean section, Dexmedetomidine