ABSTRACT

Aim: To compare the effectiveness of hyperbaric bupivacaine with isobariclevobupivacaine for cesarean section. Study design: Randomized control trial

Place & duration of study: Department of Anaesthesia, Doctors Trust Teaching Hospital, Sargodha from 1st July 2019 to 31st March 2020.

Methodology: Sixty patients have been included in this study for lower segment cesarean section. The age of the patient was between 20 to40 years. They were divided in to two groups; Group I contained 30 patients received 2 ml isobaric levobupivacaine 5mg/ml (10mg) with fentanyl 15μg, Group II, with 30 patients received hyperbaric bupivacaine 10 mg with a fentanyl 15μg. Time to block T10 was analyzed and contrasts between the two groups. Time to first rescue analgesia was recorded.

Results: The mean age was 27.84±6.33 years for Group I patients, and the mean age was 27.33±4.84 years for Group II patients. In the time of T10 sensory blockade, we found the findings were close. But we saw an important difference in time after skin closure to the first rescue analgesia. It was 273.40 minutes in Group I and 183.52 minutes for Group II.

Conclusion: Levobupivacaine and fentanyl combination give shorter block time for motors, more time to rescue analgesia as compared to hyperbaric bupivacaine in the spinal anaesthesia for cesarean section.

Keywords: Levobupivacaine, Spinal anaesthesia, Intrathecal, Bupivacaine