ABSTRACT

Aim: To determine the effectiveness of magnesium sulfate for the treatment of severe traumatic brain injury. Study design: Prospective study Place and duration of study: Department of Neurosurgery, Gambat Medical College Pir Abdul Qadir Shah Jeelani Institute of Medical Sciences Gambat from 1st January 2020 to 30th June 2020. Methodology: Fifty five patients of both genders were included in this study. Enrolled patients were aged between 20-60 years. Patients detailed demographics age, sex and body mass index were recorded after taking written consent. Glasgow coma score were recorded in this research at first day of admission in hospital and at 5th day. Results: Thirty nine (70.91%) patients were males and 16 (29.09%) patients were females. Mean age of the patient was 40.02±8.78 years with mean body mass index 26.21±9.52 kg/m2. The mean duration of the post traumatic brain injury was 7.19±1.23 hours. Mean Glasgow coma score without magnesium sulfate at first day was 6.64±1.23 but at the 5th day Glasgow coma score was 10.14±1.65. Significantly difference was observed with p value <0.0126. But significantly difference was not observed in Glasgow coma score with respect to gender and duration of diseases. Conclusion: The use of magnesium sulfate was effective for the treatment of traumatic brain injury among patients. Glasgow coma score among patients were improved by using magnesium sulfate at the 5th day. Keywords: Magnesium sulfate, Traumatic brain injury, Glasgow Coma Score (GCS)