Ali Adil Shamil, Najdat Ali Al-Kadhi, Kasim Sakran Abass

Inflammatory Markers as determinant for Acute Coronary Syndrome

Ali Adil Shamil, Najdat Ali Al-Kadhi, Kasim Sakran Abass



367




ABSTRACT

The inflammation plays a key role for development and progression of atherosclerosis, therefore acute coronary

syndrome (ACS). The study aimed to detection of inflammatory biomarker such as high sensitive C-reactive

protein(hs-CRP) and Interleukin-6 (IL-6) concentration in the serum of patients suffering from ACS. The study

carried out on 88 subjects were 60 of them were patients and 28 of them were healthy subjects considered as

control group , while 60 patients were divided into two groups each group included 30 patients were the first group

smuifllfielitreerds forof mve mnoyuosc abrldoioadl iwnfearrec tdiorna w(Mn If)r oamnd a tlhl es usbejeccotnsd t og roobutpa isnu sffeerruemd faronmd sutonrsetadb alet -a2n0g iCn°a. pTehcet osreisr u(mUA uPs)e. dT efonr

evaluation of hs-CRP levels by I-ChromCRP reader according to immunofluorescence assay and detection of IL-6

concentration by ELISA . Results of the study revealed the myocardial infarction and unstable angina patients

recorded a significant (p < 0.01) increase in the concentration of hc-CRP and IL-6 when compared with the control

group.So we concluded the inflammatory biomarkers elevated in the serum of patients that reveals the association

oKfe hysw-CorRdPs :a Andcu ItLe- 6c owriothn athrye smyanndirfoemstea,t ihoing ho fs ceanrsdiitaivce d cis-reeaascet.iv e protein, interleukine-6, myocardial infarction



Copyright © Pakistan Journal of Medical & Health Sciences 2024. All rights reserved!