Comparison between Tamsulosin and Tadalafil Versus Tamsulosin alone to treat Lower Ureteric Stones Through Medical Expulsive Therapy: a comparative study
Muhammad Tayab, Irfan Ullah Khan, Abdul Jabbar Pirzada, Ayaz Ahmad Khan, Muhammad Saqib, Kamran Munir Bajwa
649
ABSTRACT
Aim: To compare between Tamsulosin and Tadalafil versus Tamsulosin alone to
treat Lower Ureteric Stones through Medical Expulsive Therapy
Study design: Comparative study
Place
and duration:
This study was done at Ghulam Muhammad Mahar Medical college hospital
Sukkur, Pakistan from February 2021 to July 2021.
Methodology: This study was carried our in our institute
for 6 months. Patients that were having stones
of 5mm to 10mn were included in the study, because these stones are detected
easily through CT scans and ultrasound. Patients were randomly divided into two
groups each containing 86 persons. Prescription of tamsulosin of 0.3 mg and
tadalafil of 8 mg was given to group A patients and 0.3mg, tamsulosin was
prescribed to group B
Results: The stone expulsion rate was 78.0% in group A and 61.5% in group B. The
stone passage time was 1.55 vs. 2.22 weeks in group B. In 45 patients there was
no stone expulsion at the end of 3rd week of treatment. So these patients were
treated with laser lithotripsy. A comparison study of two groups showed that
group B has more episodes of flatulent pain than group A. The average need for
analgesia was more in group B than group A.
Conclusion: It is found from
this study that tamsulosin alone is less effective than tamsulosin and
tadalafil combination therapy and they both give fewer emergency room visits
and require less pain killers for the treatment of 5mm and 10mm ureteric stones.
ABSTRACT
Aim: To compare between Tamsulosin and Tadalafil versus Tamsulosin alone to
treat Lower Ureteric Stones through Medical Expulsive Therapy
Study design: Comparative study
Place
and duration:
This study was done at Ghulam Muhammad Mahar Medical college hospital
Sukkur, Pakistan from February 2021 to July 2021.
Methodology: This study was carried our in our institute
for 6 months. Patients that were having stones
of 5mm to 10mn were included in the study, because these stones are detected
easily through CT scans and ultrasound. Patients were randomly divided into two
groups each containing 86 persons. Prescription of tamsulosin of 0.3 mg and
tadalafil of 8 mg was given to group A patients and 0.3mg, tamsulosin was
prescribed to group B
Results: The stone expulsion rate was 78.0% in group A and 61.5% in group B. The
stone passage time was 1.55 vs. 2.22 weeks in group B. In 45 patients there was
no stone expulsion at the end of 3rd week of treatment. So these patients were
treated with laser lithotripsy. A comparison study of two groups showed that
group B has more episodes of flatulent pain than group A. The average need for
analgesia was more in group B than group A.
Conclusion: It is found from
this study that tamsulosin alone is less effective than tamsulosin and
tadalafil combination therapy and they both give fewer emergency room visits
and require less pain killers for the treatment of 5mm and 10mm ureteric stones.