Antibiotic Susceptibility Pattern in Isolates of Postoperative Wound Infections and Bacteriology of Surgical Site Infections: a Cross Sectional Study
Osama Azhar, Jamshed Bashir, Nighat Ghias, Javeria Farid, Raja Muhammad Adeel Khan, Junaid Zaman
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ABSTRACT
Aim: The goal of this research was to look at the
microorganisms that cause infections on surgical site & their antibiotic
susceptibility patterns.
Study design: Cross sectional study
Place & duration: This study was
conducted at National Hospital and Medical Center
Lahore, Pakistan from December 2019 to December 2020
Methodology: Surgical site infection samples were taken
from patients who complained of post-operative discomfort, edema, drainage, and
a delayed or non-healing wound. Following routine protocol, two swabs were
taken from each patient’s surgery site. After 18-24 hours of incubation at
35°C-37°C, the diameter of antibiotic discs was classified & measured as
sensitive (S), intermediate (I), or resistant (R)
Results: According to the data, 60 (56.07 percent) of
107 samples acquired from post-operative patients with symptoms of wound
infection indicated single isolates, 13 (12.14 percent) revealed multiple
isolates, and 34 (31.77 percent) samples revealed no bacterial growth. In all,
86 isolates have been identified, including 29 (33.7%) Gram +ve and 57 (66.3%)
Gram -ve organisms. Gram positive bacteria were very susceptible to vancomycin
& linezolid (100%) and gentamicin (79.3%), while Polymyxin B (94.7%), as
well as imipenem, were extremely vulnerable to Gram negative bacteria (79.3
percent ).
Conclusion: The most prevalent organisms identified from
the surgical site infection were Staphylococcus aureus (MAAS) and E.coli.
Microorganisms, both gram positive and gram negative, acquired resistance to
more regularly used medications such as penicillin, cephalosporins, and even
cost-effective quinolones, according to the findings of this research.
Keywords: surgical site infection, hospital acquired
infections, gram +ve bacteria, gram –ve bacteria, antibiotics
ABSTRACT
Aim: The goal of this research was to look at the
microorganisms that cause infections on surgical site & their antibiotic
susceptibility patterns.
Study design: Cross sectional study
Place & duration: This study was
conducted at National Hospital and Medical Center
Lahore, Pakistan from December 2019 to December 2020
Methodology: Surgical site infection samples were taken
from patients who complained of post-operative discomfort, edema, drainage, and
a delayed or non-healing wound. Following routine protocol, two swabs were
taken from each patient’s surgery site. After 18-24 hours of incubation at
35°C-37°C, the diameter of antibiotic discs was classified & measured as
sensitive (S), intermediate (I), or resistant (R)
Results: According to the data, 60 (56.07 percent) of
107 samples acquired from post-operative patients with symptoms of wound
infection indicated single isolates, 13 (12.14 percent) revealed multiple
isolates, and 34 (31.77 percent) samples revealed no bacterial growth. In all,
86 isolates have been identified, including 29 (33.7%) Gram +ve and 57 (66.3%)
Gram -ve organisms. Gram positive bacteria were very susceptible to vancomycin
& linezolid (100%) and gentamicin (79.3%), while Polymyxin B (94.7%), as
well as imipenem, were extremely vulnerable to Gram negative bacteria (79.3
percent ).
Conclusion: The most prevalent organisms identified from
the surgical site infection were Staphylococcus aureus (MAAS) and E.coli.
Microorganisms, both gram positive and gram negative, acquired resistance to
more regularly used medications such as penicillin, cephalosporins, and even
cost-effective quinolones, according to the findings of this research.
Keywords: surgical site infection, hospital acquired
infections, gram +ve bacteria, gram –ve bacteria, antibiotics