A Comparison of Mean Time to Request for First Analgesia Post-Operatively in Functional Endoscopic Sinus Surgeries (Fess) by Using Pre-Emptive Paracetamol Versus Intraoperative Paracetamol
Imran Ali, Nadir Nazir, Muhammad Arshed, Ali Asgher, Arif Iftikhar, Aqil Qayoom
608
ABSTRACT
Objective: To compare mean time required to request
for first analgesia post-operatively in functional endoscopic sinus surgeries (FESS)
by using pre-emptive paracetamol versus intra-operative paracetamol.
Study Design: Comparative Observational Study.
Sampling Technique: Non probable, consecutive sampling
Place & Duartion: This Study was conducted in the
Department of Anesthesiology, Sindh employee’s social security hospital landhi
Karachi, From June, 2018 to January, 2019.
Materials and Methods: In this study 64 patients of both
genders included. 36 patients were male and 28 were females. They were aged
between 18 and 70 years. This study was conducted from June, 2018 to January,
2019. Patients were distributed into two different groups, Group-1 (pre-emptive
paracetamol) and Group-2 (intra-operative paracetamol). 32 patients were
included in each group. In Group-1 (pre-emptive paracetamol), patients received
1 Gm. I/V paracetamol, 15 minutes prior to induction of general anesthesia and
in Group-2 (intra-operative paracetamol), patients received 1gm. I/V
paracetamol just before removal of endotracheal tube. Post-operatively patients
were observed in Post-Anesthesia Care Unit (PACU) with standard monitoring. Time
for first request for analgesia in minutes was noted.
Result: SPSS 16 version used for statistical
analysis. Chi squire test applied. Mean age of in pre-emptive paracetamol group
(group-1) was 51.53 + 18.90 years and mean age of patients in intra-operative
paracetamol group, was 50.43 + 19.10 years (p-value 0.819). Mean weight of
patients in pre-emptive paracetamol was 66.65 + 10.74 kg and mean weight of the
patients in intra-operative paracetamol was 67.71 + 10.78 kg. (P-value was
0.694). ASA status 1 was found in 36 (56.30%) patients and ASA status II was
found in 28 (43.80%) patients. Mean time required for first analgesia in
pre-emptive paracetamol group was 192.90 + 8.70 minutes and mean time required
for first analgesia in intra-operative paracetamol group was 163.93 + 13.57
minutes and p-value found < 0.001 (significant).
Conclusion: Significant variance was observed in the
mean time required to request for first analgesia post-operatively in
functional endoscopic sinus surgeries (FESS) by using pre-emptive paracetamol
versus intra-operative paracetamol.
Keywords: pre-emptive versus intraoperative
paracetamol, functional endoscopic sinus surgeries, time required to request
for first analgesia post-operatively.
ABSTRACT
Objective: To compare mean time required to request
for first analgesia post-operatively in functional endoscopic sinus surgeries (FESS)
by using pre-emptive paracetamol versus intra-operative paracetamol.
Study Design: Comparative Observational Study.
Sampling Technique: Non probable, consecutive sampling
Place & Duartion: This Study was conducted in the
Department of Anesthesiology, Sindh employee’s social security hospital landhi
Karachi, From June, 2018 to January, 2019.
Materials and Methods: In this study 64 patients of both
genders included. 36 patients were male and 28 were females. They were aged
between 18 and 70 years. This study was conducted from June, 2018 to January,
2019. Patients were distributed into two different groups, Group-1 (pre-emptive
paracetamol) and Group-2 (intra-operative paracetamol). 32 patients were
included in each group. In Group-1 (pre-emptive paracetamol), patients received
1 Gm. I/V paracetamol, 15 minutes prior to induction of general anesthesia and
in Group-2 (intra-operative paracetamol), patients received 1gm. I/V
paracetamol just before removal of endotracheal tube. Post-operatively patients
were observed in Post-Anesthesia Care Unit (PACU) with standard monitoring. Time
for first request for analgesia in minutes was noted.
Result: SPSS 16 version used for statistical
analysis. Chi squire test applied. Mean age of in pre-emptive paracetamol group
(group-1) was 51.53 + 18.90 years and mean age of patients in intra-operative
paracetamol group, was 50.43 + 19.10 years (p-value 0.819). Mean weight of
patients in pre-emptive paracetamol was 66.65 + 10.74 kg and mean weight of the
patients in intra-operative paracetamol was 67.71 + 10.78 kg. (P-value was
0.694). ASA status 1 was found in 36 (56.30%) patients and ASA status II was
found in 28 (43.80%) patients. Mean time required for first analgesia in
pre-emptive paracetamol group was 192.90 + 8.70 minutes and mean time required
for first analgesia in intra-operative paracetamol group was 163.93 + 13.57
minutes and p-value found < 0.001 (significant).
Conclusion: Significant variance was observed in the
mean time required to request for first analgesia post-operatively in
functional endoscopic sinus surgeries (FESS) by using pre-emptive paracetamol
versus intra-operative paracetamol.
Keywords: pre-emptive versus intraoperative
paracetamol, functional endoscopic sinus surgeries, time required to request
for first analgesia post-operatively.