Aim: To determine the frequency of Hepatitis C virus infection in confirmed cases of ischemic heart disease.

Material and Methods:

Study design: Cross sectional descriptive study.

Study Place and Duration: The study was done at department of medicine, Services hospital Lahore over a period of 6 months after approval of Synopsis (December 7, 2017 till June 7, 2108).This descriptive cross sectional study was conducted from 15 June to December 2019 in the Radiology Department of Avicenna Medical College. A total of 90 ultrasounds undertaken at the Gynecological Ultrasound Unit. A total of 32 patients with functioning ovarian cysts were included. A total of 46 individuals with benign tumors and 9 patients with malignant cysts were included in the control group. The remaining patients were not followed up on and were treated at a different center. The majority of the patients had issues with their menstrual cycle and pain.

Data Collection Procedure:  All 291 patients meeting selection criteria were taken after approval of synopsis in this study. All data was taken from medical departments of SIMS after written informed consent along with their biodata like name, age, along with contact details. A sample of appropriate size of blood was drawn out with help of senior staff nurse in aseptic / sterilized container and was sent out to hospital laboratory for the analysis of HCV. The diagnosis of HCV was done as per operational definition.

Results: The mean age of cases was 53.36 ± 15.21 with minimum and maximum age as 28 and 80 years. There were 200(68.7%) male and 91(31.3%) female cases with 2.20:1 male to female ratio. There were 100(34.4%) cases who belonged to lower, 116(39.9%) belonged to middle and 75(25.8%) cases belonged to upper class. According to operational definition, 80(27.5%) of the cases had Hepatitis C while in 211(72.5%) cases Hepatitis C was negative.

Conclusion: It is concluded that the prevalence of Hepatitis C virus was positive in 27.5% that’s too high, so it must be ensure in all cases IHD to screen and diagnosis of HCV. If they remained undiagnosed then they may develop related complications such as severe coronary lesions that can further elevate the risk of cardiac morbidity and mortality.

Keywords: Cardiovascular disease, ischemia heart diseases, risk factor, extra hepatic manifestations