Maternal and Fetal Outcome among Women having Pre Eclampsia with Hyperuricemia
Shamama Rahim, Shazia Mahmood Awan, Faiza Khanum, Erum Pervaiz, Saira Saeed, Neelum Zahir
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ABSTRACT
Objective: To find out the frequency of some common maternal and fetal outcomes among
women having pre eclampsia with hyperuricemia.
Study
design: Cross sectional study.
Place and
duration of study: Department of Obstetrics and Gynaecology, Hayatabad Medical Complex, Peshawar from
April 2019 to Oct 2019.
Patients
and methods: A total of 161 women with singleton pregnancy
irrespective of gravity and party, in age group ranging from 20-35 years having
pre eclampsia with hyperuricemia were included in consective manner. All patients
signed informed written consent for study and its outcome. Detailed history
taking and examination were performed and standard lab investigations were sent.
All patients were followed up till 40th day of delivery for maternal
(caesarean section, eclampsia and maternal death) and fetal outcome [intrauterine
fetal death, (small for gestational age) SGA and APGAR score].
Data was analyzed using SPSS version 20.
Results: Maternal complications in patients of pre eclampsia with hyperuricemia were
eclampsia 15.5%, caesarean section 18% and death 19.3%. Fetal complications included
SGA 11.8%, intrauterine death 16.8% and APGAR score at 5 minutes 24.2%. The mean
age and standard deviation of sample were 28.4 + 4.8 years, mean gravidity (2.7±1.1),
mean parity (2.4±0.9) and mean BMI (24.37±2.4 kg/m2).
Conclusion: Hyperuricemia in pre-eclampsia is a poor prognostic factor with increased
maternal and fetal deaths, worsening of pre eclampsia to eclampsia and low APGAR
scores of fetus.
Key words: Pre eclampsia, hyperuricemia, maternal death, caesarean section, small for
gestational age, APGAR score.