Comparison of Mean Consumption of Postoperative Analgesia with Intravenous Lidocaine Versus Normal Saline in patients Undergoing Laparoscopic Surgery
Naveed Ahmed Durrani, Sohail Iqbal, Sumara Tabassam, Zakariya Rashid, Sohail Nasir, Abdul Quddus, Mufassar Nishat
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ABSTRACT
Aim: To compare the
mean postoperative opioid consumption in patients with and without
perioperative intravenous lidocaine undergoing
laparoscopic surgery
Methodology: The study, which took place at Idrees
Teaching Hospital in Sialkot and was approved by the Ethical Committee, lasted
six months. A random sample of 100 laparoscopic procedures was used in this
study. That was all we required. The patients were separated into two groups
according to their lot number. To begin, patients in group A received a
1.5mg/kg bolus of lidocaine, which was then followed by a continuous infusion
of lidocaine at a rate of 2mg/kg/hr until the procedure was completed. All
treatments were conducted in 60 minutes by a single surgical team. The intake
of opioids persisted for 24 hours.
Results: The total number of patients in this trial
was 49.3410.30. Male patients constituted 20% of the total population, with
females accounting for the remaining 80%.In the lidocaine group, the mean dose
was 81.8017.01mg, while the mean dose in the saline group was 89.3517.74mg.
There was a significant difference in opioid use between the lidocaine and
control groups (p-value=0.032).
Conclusion: According to the findings of the study,
lidocaine reduces overall opioid use following surgery.
Keywords: Postoperative Opioids, Analgesia, and Pain
Management
ABSTRACT
Aim: To compare the mean postoperative opioid consumption in patients with and without perioperative intravenous lidocaine undergoing laparoscopic surgery
Methodology: The study, which took place at Idrees
Teaching Hospital in Sialkot and was approved by the Ethical Committee, lasted
six months. A random sample of 100 laparoscopic procedures was used in this
study. That was all we required. The patients were separated into two groups
according to their lot number. To begin, patients in group A received a
1.5mg/kg bolus of lidocaine, which was then followed by a continuous infusion
of lidocaine at a rate of 2mg/kg/hr until the procedure was completed. All
treatments were conducted in 60 minutes by a single surgical team. The intake
of opioids persisted for 24 hours.
Results: The total number of patients in this trial
was 49.3410.30. Male patients constituted 20% of the total population, with
females accounting for the remaining 80%.In the lidocaine group, the mean dose
was 81.8017.01mg, while the mean dose in the saline group was 89.3517.74mg.
There was a significant difference in opioid use between the lidocaine and
control groups (p-value=0.032).
Conclusion: According to the findings of the study,
lidocaine reduces overall opioid use following surgery.
Keywords: Postoperative Opioids, Analgesia, and Pain
Management