Histopathological differences based on method of biopsy: comparison between needle and radical prostatectomy
Muhammad Asif, Faiza Irshad, Saima Batool, Muhammad Sohail, Farhan Jamshed, Abdul Quddus, Mufassar Nishat
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ABSTRACT
Background: Prostate
cancer is the second most common male cancer. Prostate cancer is diagnosed via
a digital rectal exam, ultrasonography, and serum prostate specific antigen.
Dr. Donald Gleason devised a prostate cancer grading system over 50 years ago.
This system is still viable with modifications. The ISUP updated in 2005 and
2015. Gleason score and prognosis in prostatectomy stuff Gleason score, tumor
volume, and tumor laterality were compared. nephroscopy and prostate
Method: The study
comprised 42 men with biopsy and prostatectomy materials. Gleason's grade. The
new method graded tumors. Between october2019 and October 2021, 42 individuals
with prostate cancer were needle biopsy diagnosed and treated with RP. Tumor
volume was measured by the number of positive blocks. A significant difference
in diagnosed by digital imaging, serum prostate specific antigen, and needle
biopsy. Gleason score, location, and volume are unknown tumor features.
Result: Gleason
score, tumor volume, and laterality between needle biopsy and prostatectomy
materials Gleason score and tumor volume enhanced concordance.
Conclusion:
For a
prostate cancer diagnosis, a digital exam, serum PSA and needle biopsy are
quite sensitive. Lesser known tumor characteristics include Gleason score,
location, and volume.
Keywords: Prostate,
Adenocarcinoma, Needle biopsy, Radical prostatectomy, Gleason score
ABSTRACT
Background: Prostate
cancer is the second most common male cancer. Prostate cancer is diagnosed via
a digital rectal exam, ultrasonography, and serum prostate specific antigen.
Dr. Donald Gleason devised a prostate cancer grading system over 50 years ago.
This system is still viable with modifications. The ISUP updated in 2005 and
2015. Gleason score and prognosis in prostatectomy stuff Gleason score, tumor
volume, and tumor laterality were compared. nephroscopy and prostate
Method: The study
comprised 42 men with biopsy and prostatectomy materials. Gleason's grade. The
new method graded tumors. Between october2019 and October 2021, 42 individuals
with prostate cancer were needle biopsy diagnosed and treated with RP. Tumor
volume was measured by the number of positive blocks. A significant difference
in diagnosed by digital imaging, serum prostate specific antigen, and needle
biopsy. Gleason score, location, and volume are unknown tumor features.
Result: Gleason
score, tumor volume, and laterality between needle biopsy and prostatectomy
materials Gleason score and tumor volume enhanced concordance.
Conclusion:
For a
prostate cancer diagnosis, a digital exam, serum PSA and needle biopsy are
quite sensitive. Lesser known tumor characteristics include Gleason score,
location, and volume.
Keywords: Prostate,
Adenocarcinoma, Needle biopsy, Radical prostatectomy, Gleason score