Sohani Anwer, Sumaiya Aziz, Hiba Arshad Shaikh, Shamaila Shamaun


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ABSTRACT

Objective: To determine the association between Intra Uterine Fetal Demise (IUFD)/ Still Birth (SB) and factors associated with it in patients visiting at tertiary care hospital in Karachi.

Study Design: Observational Case Control Study

Place and Duration: This study was conducted in the department of Obstetrics & Gynecology, Aga Khan University Hospital (AKU), Karachi, Pakistan. Duration was six months from September 26, 2018 to March 25, 2019.

Materials and Methods: All patients who fulfilled the inclusion criteria were included in the study. Women with (Intra Uterine Fetal Demise/ Still Birth) were enrolled as cases and women with live Birth were enrolled as control group. Informed consent was taken after explaining the procedure, risks and benefits of the study. Associated factors such as pre-eclampsia, fetal growth restriction, gestational diabetes mellitus, obstetric cholestasis, antepartum hemorrhage, were taken from the antenatal record to assess the association with IUFD. All the collected data were entered into the proforma attached at the end and used electronically for research purpose.

Results: Mean±SD of age in case was 26.65±3.98 with C.I (25.78----27.51) and in control was 27.60±3.90 with C.I (26.75----28.44) years. In group wise distribution of gender of fetus 42 (50.0%) boys and 42 (50.0%) girls were enrolled in case and 34 (40.47%) boys and 50 (59.53%) girls were included in control group. Rate of growth restriction was 2 times more likely in cases as compare to control with [OR 2.00] while the rate of antepartum hemorrhage was 1.2 times more likely in cases as compare to control with [OR 1.205] and P value found to be non-significant i.e.(P=0.223 and 0.575) in growth restriction and antepartum hemorrhage respectively.

Conclusion: It is to be concluded that, the incidence of intrauterine fetal deaths in our population is higher than that reported from developed countries. This is associated with preeclampsia, obstetric cholestasis, diabetes mellitus pregnancy-induced hypertension, illiteracy and low socioeconomic status.

Keywords: Still Birth, Parity,Intra Uterine Fetal Demise



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