Correlation of Serum Sodium Level with Severity of Hepatic Encephalopathy
Jahan Sardar, Muhammad Asim, Muhammad Nadeem, Muhammad Ilyas Khan, Tahira Qamash, Ghulam Farooq
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ABSTRACT
Introduction: One of the most serious complications of liver
failure is the development of the condition known as hepatic encephalopathy
(HE), which affects the personality, cognitive and motor functions of patients.
The sodium level in serum in hepatic encephalopathy has been studied and has
been found lower than the normal individual.
Objective: To find out the
frequency of hyponatremia in patients with hepatic enchapalopathy
Methodology: This Descriptive
Cross-Sectional study was conducted at the Department of Medicine, Hayatabad
Medical Complex, Peshawar from October 2020 to April 2021. In this study a
total of 170 patients were observed to
find out the frequency of hyponatremia in patients with hepatic enchapalopathy.
Results: Based on grades of hyponatremia among 170
patients, Mild (130-134 mmol/L) was observed in 101(59.4%), Moderate: 125-129
mmol/L in 50(29.4%) and profound: < 125 mmol/L was observed in 19(11.2%)
subjects. Hepatic encephalopathy was found in 91(53.5%) subjects while not
found in 79(46.5 %) subjects.
Conclusion: Chronic
liver disease is linked to abnormal serum sodium concentrations, according to
our findings. The most prevalent anomaly in this research is hyponatremia.
In comparison to individuals with blood sodium levels of greater
than 136mEq/L, patients with serum sodium levels of less
than 135mEq/L had a higher prevalence of encephalopathy. Patients with a
serum sodium content less than 130 mEq/L are the most severely affected.
Key words: Hyponatremia; Hepatic enchapalopathy; Serum sodium
level
ABSTRACT
Introduction: One of the most serious complications of liver
failure is the development of the condition known as hepatic encephalopathy
(HE), which affects the personality, cognitive and motor functions of patients.
The sodium level in serum in hepatic encephalopathy has been studied and has
been found lower than the normal individual.
Objective: To find out the
frequency of hyponatremia in patients with hepatic enchapalopathy
Methodology: This Descriptive
Cross-Sectional study was conducted at the Department of Medicine, Hayatabad
Medical Complex, Peshawar from October 2020 to April 2021. In this study a
total of 170 patients were observed to
find out the frequency of hyponatremia in patients with hepatic enchapalopathy.
Results: Based on grades of hyponatremia among 170 patients, Mild (130-134 mmol/L) was observed in 101(59.4%), Moderate: 125-129 mmol/L in 50(29.4%) and profound: < 125 mmol/L was observed in 19(11.2%) subjects. Hepatic encephalopathy was found in 91(53.5%) subjects while not found in 79(46.5 %) subjects.
Conclusion: Chronic liver disease is linked to abnormal serum sodium concentrations, according to our findings. The most prevalent anomaly in this research is hyponatremia. In comparison to individuals with blood sodium levels of greater than 136mEq/L, patients with serum sodium levels of less than 135mEq/L had a higher prevalence of encephalopathy. Patients with a serum sodium content less than 130 mEq/L are the most severely affected.
Key words: Hyponatremia; Hepatic enchapalopathy; Serum sodium level