Prevalence of Tumors in the Posterior Cerebral Fossa in Children and Adults, as well as their Histological Kinds: a Cross-Sectional Study
Irfanullah Shah, Muhammad Aslam Shaikh, Khalid Mehmood
690
ABSTRACT
Aim: To determine the prevalence of posterior fossa tumors in
children and adults, as well as their histological kinds.
Study design: A cross-sectional study
Place and
duration: From February 2012 to
January 2019, the Department of Neurosurgery at Riyadh Care Hospital
Methodology: We undertook a descriptive analysis of
patients with posterior fossa space-occupying lesions. The neurosurgical
intervention was done in all of the instances due to the critical location.
Specimens were sent for histological evaluation after surgery. The data from
these patients, as well as histology reports, were examined. The data was
analyzed using SPSS version 21.
Results: Males made up 57.14 percent (n=48) of the 84
patients, while children made up 41.66 percent (n=35). The most common tumor
was schwannoma, seen in 34.52 percent (n=29) of cases, 72.41 percent of adults,
and 27.58 % of children. In 22.61 %, 15.47 %, and 14.28 % of cases, meningioma,
pilocytic astrocytoma (PCA), and Meduloblastoma were found, respectively.
Metastasis was only seen in adults, and malignant round blue cell tumors were
only found in children.
Astrocytoma and
schwannoma were prevalent in adults. Children were more likely to develop Meduloblastoma,
Pilocytic astrocytoma, and malignant round blue cell tumors.
Conclusion: High-grade Astrocytoma
and Schwannoma are dominantly present in adults. Malignant round blue cell
tumor, Pilocytic astrocytoma Medulloblastoma is more prevalent in children.
Metastasis was only observed in adults. Because of their location, risk of
excision, and involvement of the brain stem structures and fourth ventricle,
posterior fossa tumors are widely known for their significant morbidity and
mortality. Early diagnosis is now possible due to modern diagnostic and therapy
technologies, which help to lower mortality rates and improve postoperative
prognosis.
Keywords: posterior cerebral fossa tumors, children,
adults
ABSTRACT
Aim: To determine the prevalence of posterior fossa tumors in
children and adults, as well as their histological kinds.
Study design: A cross-sectional study
Place and
duration: From February 2012 to
January 2019, the Department of Neurosurgery at Riyadh Care Hospital
Methodology: We undertook a descriptive analysis of
patients with posterior fossa space-occupying lesions. The neurosurgical
intervention was done in all of the instances due to the critical location.
Specimens were sent for histological evaluation after surgery. The data from
these patients, as well as histology reports, were examined. The data was
analyzed using SPSS version 21.
Results: Males made up 57.14 percent (n=48) of the 84
patients, while children made up 41.66 percent (n=35). The most common tumor
was schwannoma, seen in 34.52 percent (n=29) of cases, 72.41 percent of adults,
and 27.58 % of children. In 22.61 %, 15.47 %, and 14.28 % of cases, meningioma,
pilocytic astrocytoma (PCA), and Meduloblastoma were found, respectively.
Metastasis was only seen in adults, and malignant round blue cell tumors were
only found in children.
Astrocytoma and
schwannoma were prevalent in adults. Children were more likely to develop Meduloblastoma,
Pilocytic astrocytoma, and malignant round blue cell tumors.
Conclusion: High-grade Astrocytoma
and Schwannoma are dominantly present in adults. Malignant round blue cell
tumor, Pilocytic astrocytoma Medulloblastoma is more prevalent in children.
Metastasis was only observed in adults. Because of their location, risk of
excision, and involvement of the brain stem structures and fourth ventricle,
posterior fossa tumors are widely known for their significant morbidity and
mortality. Early diagnosis is now possible due to modern diagnostic and therapy
technologies, which help to lower mortality rates and improve postoperative
prognosis.
Keywords: posterior cerebral fossa tumors, children,
adults