Frequency of Prostate Cancer in Men with Low Percent Free Prostate Specific Antigen in the Serum
Mehnaz Jabeen, Rabeea Saleem, Shireen Piyarali, Pardeep Kumar Maheshwari, Syed Rafiuddin Uddin Shah, Asad Shahzad Hasan
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ABSTRACT
Introduction: Prostate cancer is
the utmost communal type of cancer in adult men. Assessment of serum total
prostate specific antigen (PSA) is broadly cast-off as a screening assistance
in the prompt diagnosis of cancer of prostate. Irrespective of the prostate
size or patient’s age, 25% cut off value is set or less free PSA level in
percentage is suggested for cases with values of PSA amid 4.1 and 10 ng/ml;
This helps in detecting prostate cancers in 95% of cases and prevent 20% of
unnecessary biopsies. The greater the free PSA percentage, the less jeopardy of
cancer. This analysis was designed to evaluate the incidence of prostate cancer
in patients with a low percentage of free PSA. If the scale is found to be
higher, aggressive strategies and early treatment can lead to good progress.
Aim: To determine the frequency of
prostate cancer in males with a low percentage of serum free PSA.
Study Design: This is a
descriptive, cross-sectional study lasting 6 months from July 2020 to December
2020 at the Urology Department of the Sindh Institute of Urology and
Transplantation.
Subject and method: 149 total individuals
with symptoms of lower urinary tract were included in the research. All
patients who came to the urology clinic (OPD); free PSA were examined with the
same technique as the surgical patient and the result was recorded as proforma.
Results: - The prostate cancer Incidence in males with decreased
free serum PSA in percentage is noted in 128(85.91%) patients.
Conclusions: Our study showed
that prostate-specific free antigen plays an important role in the analysis of cancer of prostate.
Keywords: Serum prostate specific antigen, Prostate cancer, percentage of free PSA
ABSTRACT
Introduction: Prostate cancer is
the utmost communal type of cancer in adult men. Assessment of serum total
prostate specific antigen (PSA) is broadly cast-off as a screening assistance
in the prompt diagnosis of cancer of prostate. Irrespective of the prostate
size or patient’s age, 25% cut off value is set or less free PSA level in
percentage is suggested for cases with values of PSA amid 4.1 and 10 ng/ml;
This helps in detecting prostate cancers in 95% of cases and prevent 20% of
unnecessary biopsies. The greater the free PSA percentage, the less jeopardy of
cancer. This analysis was designed to evaluate the incidence of prostate cancer
in patients with a low percentage of free PSA. If the scale is found to be
higher, aggressive strategies and early treatment can lead to good progress.
Aim: To determine the frequency of
prostate cancer in males with a low percentage of serum free PSA.
Study Design: This is a
descriptive, cross-sectional study lasting 6 months from July 2020 to December
2020 at the Urology Department of the Sindh Institute of Urology and
Transplantation.
Subject and method: 149 total individuals
with symptoms of lower urinary tract were included in the research. All
patients who came to the urology clinic (OPD); free PSA were examined with the
same technique as the surgical patient and the result was recorded as proforma.
Results: - The prostate cancer Incidence in males with decreased
free serum PSA in percentage is noted in 128(85.91%) patients.
Conclusions: Our study showed
that prostate-specific free antigen plays an important role in the analysis of cancer of prostate.
Keywords: Serum prostate specific antigen, Prostate cancer, percentage of free PSA