Predictive Value of Maternal Beta Human Chorionic Gonadotropin for Risk Assessment of Hypertensive Disorders of Pregnancy
Shakila Yasmin, Sara Reza, Aisha Javed, Amna Anum, Shahnaz Noor, Irum Noor
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ABSTRACT
Objective: This study was conducted to find out if measuring
levels of beta HCG in early 2nd trimester can accurately predict HDP
occurrence.
Methods: This was a prospective
observational study was conducted from August 2020 to September 2021 at OPD/IPD
of Gynae Unit-II of Bahawal Victoria Hospital, Bahawalpur. The tests were done
at Pathology Department, Quaid-e-Azam Medical College, Bahawalpur. Beta HCG
levels of total 180 pregnant females who were in their second trimester (14-20)
were assessed.
Results: Out of 180 study subjects, 157 cases remained
normotensive and 23 patients got hypertensive
disorders of pregnancy. Out of these 23 patients , twelve patients had mild hypertensive disease while eleven patients
had severe disease. We noticed a
significantly raised serum β hCG levels in females with htn disorder of
pregnancy as compared to normotensive pregnant females.
Conclusion: The study indicated that pregnant women with
raised beta HCG levels in early pregnancy are at an increased risk of adopting gestational
hypertension and related disorders so beta HCG in second trimester can be used
as a good predictive test for HDPs.
Keywords: Pregnancy, Beta HCG, Hypertensive pregnancy disorders, trimester, hypertension