Comparison of Severity of Disease and ICU Stay among Vaccinated and Non-Vaccinated Covid 19 Patients
Waseem Babur, Naveed Noor Khan, Muhammad Bilal Abdullah
1441
ABSTRACT
Objective: The purpose of this
study is to examine the severity of illness and length of ICU stay in covid-19
patients who have received vaccination vs those who have not received
vaccination.
Study Design: A Retrospective/ Comparative study
Place and
Duration: King Salman Armed Forces Hospital
Tabuk KSA. Nov 2021-July 2021
Methods: This research included 160 individuals of both sexes who
had coronavirus illness. Patients were between the ages of 18 and 75. After
obtaining informed written permission, demographic data on patients, such as
age, gender, BMI, place of residence were gathered. It was determined that
the coronavirus was present in all instances by RT-PCR. Two sets of patients
were admitted to COVID 19 ward, and they were subsequently separated. Both groups
were underwent for X-ray of chest. Two groups were formed: one with 80
vaccinated patients and the other with 80 unvaccinated individuals. In both
groups, the prevalence of co-morbidities was evaluated. Both groups' recovery
and results were assessed by looking at things like mortality and the severity
of the condition. Complete data was analzsed using SPSS 22.0.
Results: Among 160 cases, 100 (62.5%) were males and 60 (37.5%)
females in this study. There was no any significantly difference between both
groups related to age and body mass index. We found severity of disease among
non-vaccinated patients was significantly high with p value <0.05.Diabetes
mellitus and hypertension were the most common comorbidities among all cases.
Frequency of interstitial infiltrates was found in 55 (68.8%) in group I and 60
(75%) in group II. In both groups, fever, cough, and dyspnea were the most
prevalent symptoms. Frequency of discharged patients in group I was greater 66
(82.5%) as compared to non-vaccinated 29 (36.3%). ICU stay and mortality was
significantly higher in group II 16 (20%),24 (30%) as compared to group I with
p value <0.05.
Conclusion: This
research found that immunization against coronavirus illness is both effective
and useful in lowering the severity of the condition. However, vaccination may
lower the incidence of bad outcomes (ICU stay) and people should be made aware
of the necessity of being vaccinated immediately.
Keywords: Mortality, COVID 19, Vaccination, ICU stay
ABSTRACT
Objective: The purpose of this
study is to examine the severity of illness and length of ICU stay in covid-19
patients who have received vaccination vs those who have not received
vaccination.
Study Design: A Retrospective/ Comparative study
Place and
Duration: King Salman Armed Forces Hospital
Tabuk KSA. Nov 2021-July 2021
Methods: This research included 160 individuals of both sexes who
had coronavirus illness. Patients were between the ages of 18 and 75. After
obtaining informed written permission, demographic data on patients, such as
age, gender, BMI, place of residence were gathered. It was determined that
the coronavirus was present in all instances by RT-PCR. Two sets of patients
were admitted to COVID 19 ward, and they were subsequently separated. Both groups
were underwent for X-ray of chest. Two groups were formed: one with 80
vaccinated patients and the other with 80 unvaccinated individuals. In both
groups, the prevalence of co-morbidities was evaluated. Both groups' recovery
and results were assessed by looking at things like mortality and the severity
of the condition. Complete data was analzsed using SPSS 22.0.
Results: Among 160 cases, 100 (62.5%) were males and 60 (37.5%)
females in this study. There was no any significantly difference between both
groups related to age and body mass index. We found severity of disease among
non-vaccinated patients was significantly high with p value <0.05.Diabetes
mellitus and hypertension were the most common comorbidities among all cases.
Frequency of interstitial infiltrates was found in 55 (68.8%) in group I and 60
(75%) in group II. In both groups, fever, cough, and dyspnea were the most
prevalent symptoms. Frequency of discharged patients in group I was greater 66
(82.5%) as compared to non-vaccinated 29 (36.3%). ICU stay and mortality was
significantly higher in group II 16 (20%),24 (30%) as compared to group I with
p value <0.05.
Conclusion: This
research found that immunization against coronavirus illness is both effective
and useful in lowering the severity of the condition. However, vaccination may
lower the incidence of bad outcomes (ICU stay) and people should be made aware
of the necessity of being vaccinated immediately.
Keywords: Mortality, COVID 19, Vaccination, ICU stay