Objective: To determine the effectiveness of the structured rehabilitation program on knee pain and function in patients with a total knee replacement.

Methodology: A randomized controlled trial conducted at Horizon Hospital Lahore. Twenty six patients were randomly allocated to experimental and control group. Experimental group was treated with structured rehabilitation program and conventional exercises while control group was treated with conventional exercises alone. Outcome measuring tools were numeric pain rating scale, Western Ontario McMaster Universities Osteoarthritis Index (WOMAC) and goniometer. All the patients received 16 sessions of treatment. Data was collected at baseline and at the end of 4th week.

Results: Outcome measures numeric pain rating scale, Western Ontario McMaster Universities Osteoarthritis Index (WOMAC) and goniometer showed significant results (p<0.05) after treatment in both groups but mean values showed more improvement in experimental group treated with structured rehabilitation program.

Conclusion: This study concluded that structured rehabilitation program had better effects on pain, function and range of motion in patients with knee arthroplasty.

Keywords: Arthroplasty, Replacement, Knee, Knee osteoarthritis, Range of motion, exercise therapy