Background: Renal failure affects about 1.1 million people worldwide, and the number is growing at a frequency of 7% each year. Anemia is a prevalent complication of chronic renal disease, which is linked to a high rate of morbidity.

Objective: To assess the impact of haemodialysis on haematological parameters in patients with chronic kidney failure

Methodology: This study design was cross-sectional, carried out at the Institute of Kidney Disease, Hayatabad Medical Complex, Peshawar for a period of six months from July 2021 to December 2021. Totally, 160 chronic kidney failure patients were included in the current research work. All the blood samples taken were analyzed by using automatic hematology analyzer (Sysmex XE-21 analyzers) for complete blood count. Data analysis was carried out by using IBM SPSS version 24.

Results: Based on the stages of anemia, amongst 160 patients, 17 (10.63%) patients were normal whereas the mild, moderate and severe anemia was observed in 64 (40%), 72 (45%) and 7 (4.68%) patients respectively. In comparison to pre-dialysis, significant increase was observed in RBC, RDW HB, MCHC and HCT after post-dialysis whereas significant decrease in TLC, MCV and non-significant decrease in Platelets was observed after post-dialysis in chronic kidney failure patients.

Conclusion: Our study concludes that haematological parameters are significantly affected by the hemodialysis. For hemodialysis patients, hemoglobin is an important risk factor. Our study recommends that all the patients should be screened for hematological parameters before hemodialysis

Keywords: Haemodialysis; Haematological parameters; chronic kidney failure