Introduction: Immune-mediated diseases such as celiac disease and inflammatory bowel disease (IBD) are still unable to be fully recognized, although the etiologic factors are multifactorial.

Material and Method: This meta-analysis taken literature based on full-text English journals published in the last 20-years ago (range 2002-2022). This article aims to discuss one-way or two-way connection between IBD inflammatory bowel disease and celiac disease CeD. The databases that we use in writing this article are Sage Pub, Pubmed and Google Schoolar.

Result: Several researches have presented that with IBD in patients, CeD is more common than the general population, although these results are inconsistent.

Conclusion: One of the risk factors associated with the association between IBD and CeD is genetic susceptibility, which can be clearly identified from a previous family history of the disease.

Keyword: Celiac Disease; Crohn’s Disease; IBD (Inflammatory Bowel Disease); Ulcerative Colitis