Comparison of Vacuum Assisted Closure (VAC) Therapy Versus Conventional Dressing in the Management of Diabetic Foot Ulcer
Waleed Anjum, Sayed Zamen Ali, Mohsin Mumtaz, Muhammad Imran, Hijab Siddique, Hussain Zia
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ABSTRACT
Background: Debridement of all necrotic,
callus, and fibrous tissue is a mainstay of diabetic foot ulcer therapy, with
the primary goal of wound closure. The best topical treatment for diabetic foot
ulcers is yet unknown. To aid wound healing, a vacuum-assisted closure (VAC)
device is used.
Objective: To compare the outcome
of vacuum-assisted wound closure (VAC) versus conventional wound dressing in
diabetic foot ulcers.
Material and methods: Study
Design: Randomized
Control Trial. Setting: Department
of Surgery, Services Hospital, Lahore.Duration of Study: 6 months
i.e. from-to-Data Collection: Forty patients with diabetic foot ulcer
were included. Patients were randomly assigned in two groups. In group A, the
dressing was applied by using adhesive drape to create the airtight seal. Conventional
group received gauze dressingsoaked in saline once daily. Patients were
followed regularly for 2 weeks to check for appearance of granulation tissue.
Outcome was determined in terms of appearance of granulation tissue.
Results: In VAC group, the mean
age of patients was 42.95±9.29years. In conventional group, the mean age of
patients was 46.30±9.33years. In VAC group, there were 12 (60%) males and 8
(40%) females. In conventional group, there were 16 (80%) males and 4 (20%) females.
In VAC group, the mean duration of wound healing was 7.50±2.82days. In
conventional group, the mean duration of wound healing was 10.60±5.55days. The
difference was significant (p<0.05). In VAC group, there were 20 (100%)
patients who had treatment success. In conventional group, there were 13 (65%)
patients who had treatment success while 7 935.0%) did not have complete
healing within 2weeks. The difference was significant (p<0.05).
Conclusion: Thus, VAC is more successful in achieving granulation of tissues in
patients with diabetic foot ulcer as compared to conventional dressing
Keywords:Type II diabetes mellitus, diabetic foot ulcerations, Vacuum-assisted
wound closure, conventional dressings, Negative pressure wound therapy
ABSTRACT
Background: Debridement of all necrotic,
callus, and fibrous tissue is a mainstay of diabetic foot ulcer therapy, with
the primary goal of wound closure. The best topical treatment for diabetic foot
ulcers is yet unknown. To aid wound healing, a vacuum-assisted closure (VAC)
device is used.
Objective: To compare the outcome
of vacuum-assisted wound closure (VAC) versus conventional wound dressing in
diabetic foot ulcers.
Material and methods: Study
Design: Randomized
Control Trial. Setting: Department
of Surgery, Services Hospital, Lahore.Duration of Study: 6 months
i.e. from-to-Data Collection: Forty patients with diabetic foot ulcer
were included. Patients were randomly assigned in two groups. In group A, the
dressing was applied by using adhesive drape to create the airtight seal. Conventional
group received gauze dressingsoaked in saline once daily. Patients were
followed regularly for 2 weeks to check for appearance of granulation tissue.
Outcome was determined in terms of appearance of granulation tissue.
Results: In VAC group, the mean
age of patients was 42.95±9.29years. In conventional group, the mean age of
patients was 46.30±9.33years. In VAC group, there were 12 (60%) males and 8
(40%) females. In conventional group, there were 16 (80%) males and 4 (20%) females.
In VAC group, the mean duration of wound healing was 7.50±2.82days. In
conventional group, the mean duration of wound healing was 10.60±5.55days. The
difference was significant (p<0.05). In VAC group, there were 20 (100%)
patients who had treatment success. In conventional group, there were 13 (65%)
patients who had treatment success while 7 935.0%) did not have complete
healing within 2weeks. The difference was significant (p<0.05).
Conclusion: Thus, VAC is more successful in achieving granulation of tissues in
patients with diabetic foot ulcer as compared to conventional dressing
Keywords:Type II diabetes mellitus, diabetic foot ulcerations, Vacuum-assisted
wound closure, conventional dressings, Negative pressure wound therapy