Association Between Cytological and Histological Grading of Breast Cancer and its Usefulness in Patient Treatment
Muhammad Waqas Khan, Muhammad Bilawal Khan, Karishma Rehman, Sania Bibi, Sunia Arif Khan, Omar Aamir Aziz
1080
ABSTRACT
Introduction: Breast cancer is the
most common cancer in women throughout the globe, and the modern therapeutic
available options have been widely researched currently. For a developing
nation with limited resources, such as Pakistan, a quick, affordable, and least
invasive technique like FNAC may give useful information.
Aim: The aim of this study
was;
1 Perform and evaluate cytomorphological
classification of all breast cancer patients using the Robinson's three-tier
grading system.
2 Histopathological evaluation and
classification of all samples of MRM by using a modified BR classification
system.
3 Correlation of histo-morphological and
cytomorphological classification systems.
Place and Duration: In the Pathology
department of Khyber Teaching Hospital Peshawar for six months duration from
February 2018 to July 2018.
Material and methods: A prospective study
was conducted in which two independent observers classified all breast cancer
patients on the basis of cytology and histology of the tissue and
cyto-histological correlation.
Results: This study provided
good individual correlation and inter-observer agreement in the
cytopathological classification of breast cancer aspirates.
Conclusion: Cytopathological
classification may be useful for these patients and should therefore be
included in routine reports.
Keywords: Breast carcinoma; Cytopathology;
Robinson classification system
ABSTRACT
Introduction: Breast cancer is the
most common cancer in women throughout the globe, and the modern therapeutic
available options have been widely researched currently. For a developing
nation with limited resources, such as Pakistan, a quick, affordable, and least
invasive technique like FNAC may give useful information.
Aim: The aim of this study
was;
1 Perform and evaluate cytomorphological
classification of all breast cancer patients using the Robinson's three-tier
grading system.
2 Histopathological evaluation and
classification of all samples of MRM by using a modified BR classification
system.
3 Correlation of histo-morphological and
cytomorphological classification systems.
Place and Duration: In the Pathology
department of Khyber Teaching Hospital Peshawar for six months duration from
February 2018 to July 2018.
Material and methods: A prospective study
was conducted in which two independent observers classified all breast cancer
patients on the basis of cytology and histology of the tissue and
cyto-histological correlation.
Results: This study provided
good individual correlation and inter-observer agreement in the
cytopathological classification of breast cancer aspirates.
Conclusion: Cytopathological
classification may be useful for these patients and should therefore be
included in routine reports.
Keywords: Breast carcinoma; Cytopathology;
Robinson classification system