Muhammad Waqas Khan, Muhammad Bilawal Khan, Karishma Rehman, Sania Bibi, Sunia Arif Khan, Omar Aamir Aziz

Association Between Cytological and Histological Grading of Breast Cancer and its Usefulness in Patient Treatment

Muhammad Waqas Khan, Muhammad Bilawal Khan, Karishma Rehman, Sania Bibi, Sunia Arif Khan, Omar Aamir Aziz



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ABSTRACT

Introduction: Breast cancer is the most common cancer in women throughout the globe, and the modern therapeutic available options have been widely researched currently. For a developing nation with limited resources, such as Pakistan, a quick, affordable, and least invasive technique like FNAC may give useful information.

Aim: The aim of this study was;

1    Perform and evaluate cytomorphological classification of all breast cancer patients using the Robinson's three-tier grading system.

2    Histopathological evaluation and classification of all samples of MRM by using a modified BR classification system.

3    Correlation of histo-morphological and cytomorphological classification systems.

Place and Duration: In the Pathology department of Khyber Teaching Hospital Peshawar for six months duration from February 2018 to July 2018.

Material and methods: A prospective study was conducted in which two independent observers classified all breast cancer patients on the basis of cytology and histology of the tissue and cyto-histological correlation.

Results: This study provided good individual correlation and inter-observer agreement in the cytopathological classification of breast cancer aspirates.

Conclusion: Cytopathological classification may be useful for these patients and should therefore be included in routine reports.

Keywords: Breast carcinoma; Cytopathology; Robinson classification system



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