Levels of Electrolytes, Troponin and association of O2 saturation with D–Dimer and Ferritin in hospitalized COVID-19 patients
Muhammad Abbas, Aziz Ur Rehman, Zahoor Ahmad, Suleman Khan, Salih Noor, Rabia Mazhar, Muhammad Ubaid, Hussain Ahmad
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ABSTRACT
A cluster of atypical pneumonia cases were reported in
Wuhan china at the end of 2019. The disease was subsequently named covid-19. Later
on it spread across the globe and WHO declared it as greatest pandemic of 21st
century. Previous studies show that majority of the patients have hyponatremia,
hypokalemia and hypochloremia. Recent study also suggests that the value of D-Dimer,
ferritin and troponin I increasewhile O2 saturation drops in
covid-19 patients.A cross sectional observational study was carried out in
Peshawar Pakistan. A total of 195 patients above 18 years of age, confirmed
through real time PCR were studied. Most of the patients have normal levels of
electrolytes (Reference range of sodium 135-150mmol/L, potassium 3.5-5.1mmol/L,
chloride 96-112mmol/L)while the patients with abnormal levels includedhyponatremic
patients (having sodium level less than 135mmol/L), hyperkalemic patients (having
potassium level higher than 5.1mmol/L) and hypochloremic patients (having
chloride level less than 96mmol/L). The abnormal level of electrolytes is due
to renal abnormalities. An association of O2 saturation exists with
ferritin and D-Dimer. The level ofTroponin I raisestwofold in COVID-19 patients,
which is an important circulatory biomarker associated with myocardial injury.
Key words: COVID-19, Electrolyte
imbalance, O2 saturation, Troponin I, D-Dimer
ABSTRACT
A cluster of atypical pneumonia cases were reported in
Wuhan china at the end of 2019. The disease was subsequently named covid-19. Later
on it spread across the globe and WHO declared it as greatest pandemic of 21st
century. Previous studies show that majority of the patients have hyponatremia,
hypokalemia and hypochloremia. Recent study also suggests that the value of D-Dimer,
ferritin and troponin I increasewhile O2 saturation drops in
covid-19 patients.A cross sectional observational study was carried out in
Peshawar Pakistan. A total of 195 patients above 18 years of age, confirmed
through real time PCR were studied. Most of the patients have normal levels of
electrolytes (Reference range of sodium 135-150mmol/L, potassium 3.5-5.1mmol/L,
chloride 96-112mmol/L)while the patients with abnormal levels includedhyponatremic
patients (having sodium level less than 135mmol/L), hyperkalemic patients (having
potassium level higher than 5.1mmol/L) and hypochloremic patients (having
chloride level less than 96mmol/L). The abnormal level of electrolytes is due
to renal abnormalities. An association of O2 saturation exists with
ferritin and D-Dimer. The level ofTroponin I raisestwofold in COVID-19 patients,
which is an important circulatory biomarker associated with myocardial injury.
Key words: COVID-19, Electrolyte
imbalance, O2 saturation, Troponin I, D-Dimer