ABSTRACT

Objective: To determine the frequency of causative microorganisms and drug sensitivity in odontogenic infection.

Methodology: This cross-sectional study was done at the department of Oral and maxillofacial surgery of Liaquat University Hospital Hyderabad, during six months from August 2018 to January 2019). All subjects of 12 to 50 years of age, either gender with odontogenic infections were included. Pus was collected by transport media/swab stick and sent to the Hospital diagnostic laboratory for culture and antibiotic susceptibility, while the antibiotic sensitivity test for the isolates was performed, whereas the data was collected on pre-designed proforma and analyzed by SPSS version 26.

Results: A total of 200 patients with odontogenic infection of either gender were studied. Mean age of these cases was 51.94±8.93 years and males were in majority 63.5%. The causative microorganism includes Staphylococcus species 24.5%, Streptococcus 22.0%, Pseudomonas aeruginosa 16.0%, eubacterium 13.5%, Porphyromonas 10.5%, Prevotella 6.5%, and Fusobacterium 7.0%, while drug sensitivity includes Ampicillin 33.5%, amikacin 24.5%, Gentamicin 17.0%, Cefotaxime 14.5% and ceftazidime 10.5%. Frequency of causative microorganisms was statistically significant according to gender (p <0.05), while insignificant according to age (P->0.05).

Conclusion: As per study conclusion the staphylococcus species, streptococcus, Pseudomonas aeruginosa, eubacterium, Porphyromonas Prevotella and fusobacterium were observed to be the causative organisms in odontogenic infection. Ampicillin was the highly sensitive antibiotic drug followed by amikacin, gentamicin, cefotaxime and ceftazidime. Odontogenic infection cultures are necessary to isolate all pathogens and for successful management.