Aim: In this paper, the related factors of transient hypothyroidism in premature infants were discussed, the incidence of THOP was observed, and the risk factors were analyzed to guide future work.

Methods: From January 2017 to January 2018, 117 premature infants admitted to neonatology Department of the First Affiliated Hospital of Bengbu Medical College were selected and diagnosed with THOP in 48 cases, including 31 males and 17 females.< 1 500 g 17 cases, 1 500 ~ 2 500 g 70 cases, > 2 500 g 30 cases; Gestational age ≤32 weeks 30 cases, 33 ~ 34 weeks 37 cases, 35 ~ 36 weeks 50 cases.

Results: The incidence of THOP in different gestational age groups was statistically significant (P < 0.05).The incidence of THOP in different weight groups was statistically significant(P < 0.05).The differences of asphyxia, RDS and gestational hypertension in premature infants were statistically significant (P < 0.05), while the differences of intracranial hemorrhage, polycythemia, sepsis and hypoglycemia were not statistically significant (P > 0.05).

Conclusion: Gestational age ≤32 weeks and gestational hypertension were independent risk factors for THOP.

Key words: transient hypothyroidism; correlative factors; premature infants