Frequency of Pre-Eclampsia Induced Acute Kidney Injury
Bilal Rasool, Hina Akbar, Anees Muhammad, Muzammil Riaz Malik
2580
ABSTRACT
Aim: To determine
the frequency of preeclampsia induced acute kidney injury in patients
presenting in a tertiary care hospital.
Study design: Cross sectional study.
Study setting: Department of Nephrology, KEMU/Mayo Hospital Gynecology, Lady Atchison
Hospital Lahore,
Methodology: All 180 pregnant females having acute kidney injury as per operational
definition between 15 years to 50 years presenting in 3rd trimester
of pregnancy for delivery were included in study after taking informed consent.
Pregnant females with Blood Pressure >140/90mmHg after 20 weeks of pregnancy
and laboratory investigation i.e. proteinuria were recorded. All investigations
were done from laboratory of KEMU /Mayo hospital Lahore. After the diagnosis
was made, the patients were treated according to the guidelines in hospital
setting.
Results: In
this study, out of 180 cases, 118(65.56%) were between 15-32 years of age
whereas 62(34.44%) were between 33-55 years of age, mean±SD was calculated as
30.21±5.35 years, mean blood pressure of the patients was recorded as 154.27±108.15mmHg,
mean serum creatinine of the patients was calculated as 4.39±0.28 mg/dl,
frequency of urinary protein was recorded as 62(62.22%) while 68(37.78%) patients had no
proteinuria, frequency of preeclampsia induced AKI in pregnancy was recorded in
47(26.11%).
Conclusion: Frequency of preeclampsia induces acute kidney injury is very high and
it must be diagnosed and treated appropriately in time to reduce maternal
mortality and morbidity.
Keywords: Pre-eclampsia, acute kidney injury, frequency