Objective: To determine the association of adverse outcomes in term of mortality in patients with cirrhosis presented with coronavirus disease.

Study Design: Retrospective/observational study

Place and Duration of Study: Department of Medicine, Chandka Medical College Hospital, Larkana from 1st March 2019 to 31st December 2020.

Methodology: Two hundred and twenty covid-19 patients of both genders with or without chronic liver disease were enrolled in this study. Patients were categorized in to two groups. Group A (with cirrhosis 60 patients) and group B (without cirrhosis 60 patients). Outcomes in term of mortality between both groups were examined.

Results: There were 38 (63.33%) males and 22 (36.67%) were females with mean age 46.14±8.44 years in group A while in group B, 40 (66.67%) and 20 (33.33%) patients were males and females with mean age 45.26±9.34 years. Patients with cirrhosis had high mortality rate as compared to patients without cirrhosis (33.33% Vs 13.33%) with p-value 0.0001.

Conclusion: A significant association of adverse outcomes was found in cirrhotic patients with coronavirus disease.

Keywords: Chronic Liver Disease, Corvid-19, Mortality