ABSTRACT

Guidelines are the key points in the management of many health issues in high-standard medical centers around the world typically based on the evidence-based standards by the teamwork panels of these guidelines. The practical guidelines for laparoscopic splenectomy (LS) as a precise study in this field within the literature and surgical text books are the main objective of this research. It is believed that this Clinical Practice Guidance for LS could be feasible and fulfilsome aspects of L Sutilized by physicians, health care workers and patients. Following the grading system developed by CEBM1, the standard of evidence (LoE) is as follows:

I- Randomized Controlled Trials (RCTs, LoE 1)

II- Non-randomized controlled clinical trials (CCTs, LoE 2)

III- Case series with non-concurrent (i.e., historical) control groups (LoE 3)

IV- Simple case series (LoE 4)

The Grade of Recommendation (GoR) for each consensus statement followed the quality of scientific evidence as follows:

1. A (high quality evidence as RCTs with constantoutcomes and positive risk-benefit proportion).

2. B (moderate quality evidence as CCTs or inconsistent outcomes of high quality researches),

3. C (low quality evidence as case series or inconsistent outcomes of high quality researches with proper clinical practices in the cases of lacking or low quality evidence).