ABSTRACT

Aim: To examine the prevalence of vitamin D deficiency in patients with multiple sclerosis.

Study design: Cross-sectional/observational

Place and duration of study: Department of Medicine, Chandka Medical College Hospital, Larkana from 1st January 2020 to 30th September 2020.

Methodology: Seventy patients of both genders with ages 20 to 70 years presented with multiple sclerosis were enrolled. Patient’s demographics including age, sex, residence, disease duration and type of multiple sclerosis were recorded after taking written consent. 5ml blood sample was taken from each patient and sent to laboratory to examine vitamin D level.

Results: Forty two (60%) patients were females and 28 (40%) were males with mean age of 47.28±14.7 years. Mean duration of disease was 5.32±0.48 years. Majority of patients 40 (57.14%) had urban residency. Twenty four (34.29%) patients had low socio-economic status and 35 (50%) patients had middle status. Most common type of multiple sclerosis was relapsing remitting multiple sclerosis in 55 (78.57%) patients.

Conclusion: The frequency of deficiency of vitamin D was very high in our study population. Patients with secondary progressive multiple sclerosis had high rate of deficiency of vitamin D.

Keywords: Multiple sclerosis, Primary progressive multiple sclerosis, Relapsing remitting multiple sclerosis,